Chemical composition and antimicrobial properties of the essential oil from the leaves of Helichrysum ibityense R.Vig. & Humbert (Asteraceae)

The present work aimed to study the composition and antimicrobial properties of essential oil Helichrysum ibityense leaves (HIEO). HIEO was extracted by hydrodistillation from fresh with a yield 1.9%. It had relative density 0.9247 at 20℃, refractive index 1.4706, an optical rotation -0°33, acid 2.10 ester 54. Gas chromatography analysis/flame ionisation detection identified 17 components, representing more than 99.54% overall including 1.8-cineole (69.46%) major component, α-terpinene (4.62%), β-caryophyllene (4.39%), α-pinene (4.13%), β-pinene (2.96%), p-cymene (2.39%) γ-terpinene (2.16%). activity tested against nine pathogenic bacteria Staphylococcus aureus, pneumoniae, Streptococcus pyogenes, Clostridium perfringens, Bacillus cereus, Pseudomonas aeruginosa, Enterobacter cloacae, aerogenes, Yersinia enterocolitica, Candida albicans using Disc diffusion Microdilution assays. exhibited broad spectrum high microbial inhibition zones (IZ) ranging 12 35 mm. On most sensitive bacterium, its Minimum Inhibitory Concentration (MIC) Bactericidal (MBC) were 9.37 mg/ml 13.22 respectively. With MBC/MIC ratio 1.41, exerted bactericidal action on cereus. When administered orally mice 1000 mg/kg body weight, caused symptoms intoxication which disappeared after 24 h. These preliminary results revealed could be used treat different infectious diseases if safety will confirmed.